2026Q1
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| Torok Michael | — | 4,850,000 | Apr 11, 2025 |
| Abingworth LLP | 10% Owner | 1,599,168 | Apr 26, 2012 |
| Provoost Jonathan | EVP, Chief Legal Officer | 800,000 | Dec 5, 2023 |
| Holt Patrick | CEO | 314,426 | Jan 24, 2024 |
| Murphy Geraldine | — | 247,707 | Nov 2, 2022 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Jan 31, 2026 | Feb 3, 2026 | Berg Aaron | CEO | Sell | 46.3 | -2,298 | -1.38% | ✗ | $35.4K |
| Feb 1, 2026 | Feb 3, 2026 | Provoost Jonathan | EVP, Chief Legal Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2026 | Feb 3, 2026 | Fishman Peter L. | CFO | Sell | 46.3 | -1,318 | -10.29% | ✗ | $20.3K |
| Jan 31, 2026 | Feb 3, 2026 | Ketchum Steven B | EVP, Chief Scientific Officer | Sell | 46.3 | -2,297 | -2.76% | ✗ | $35.4K |
| Jan 31, 2026 | Feb 3, 2026 | Keenan David Paul | COO | Sell | 46.3 | -2,183 | -8.85% | ✗ | $33.7K |
| Jan 2, 2026 | Jan 6, 2026 | Fishman Peter L. | CFO | Sell | 46.3 | -1,356 | -21.07% | ✗ | $18.9K |
| Jan 2, 2026 | Jan 6, 2026 | Keenan David Paul | COO | Sell | 46.3 | -1,926 | -16.55% | ✗ | $26.9K |
| Jan 2, 2026 | Jan 6, 2026 | Provoost Jonathan | EVP, Chief Legal Officer | Sell | 46.3 | -1,488 | -40.35% | ✗ | $20.8K |
| Jan 2, 2026 | Jan 6, 2026 | Ketchum Steven B | EVP, Chief Scientific Officer | Sell | 46.3 | -2,041 | -4.97% | ✗ | $28.5K |
| Oct 31, 2025 | Keenan David Paul | COO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Aug 1, 2025 | Aug 4, 2025 | Fishman Peter L. | CFO | Sell | 47.5 | -160 | -3.86% | ✗ | $2.3K |
| Jun 26, 2025 | Jun 30, 2025 | Berg Aaron | CEO | Sell | 40.0 | -38,363 | -32.22% | ✗ | $610K |
| Apr 18, 2025 | Apr 22, 2025 | Cohen Paul | Director | Sell | 47.5 | -437 | -52.15% | ✗ | $4K |
| Apr 18, 2025 | Apr 22, 2025 | Odysseas Kostas D | Director | Sell | 47.5 | -437 | -52.15% | ✗ | $4K |
| Apr 18, 2025 | Apr 22, 2025 | Horn Keith | Director | Sell | 47.5 | -437 | -52.15% | ✗ | $4K |
| Apr 18, 2025 | Apr 22, 2025 | Sullivan Diane E. | Director | Sell | 47.5 | -437 | -52.15% | ✗ | $4K |
| Apr 18, 2025 | Apr 22, 2025 | Sterling Louis III | Director | Sell | 47.5 | -437 | -10.79% | ✗ | $4K |
| Apr 18, 2025 | Apr 22, 2025 | O'Connor Oliver | Director | Sell | 47.5 | -437 | -52.15% | ✗ | $4K |
| Apr 18, 2025 | Apr 22, 2025 | Bonfiglio Patrice Eadon | Director | Sell | 47.5 | -437 | -52.15% | ✗ | $4K |
| Apr 18, 2025 | Apr 22, 2025 | DiPaolo Mark | Director | Sell | 47.5 | -437 | -52.15% | ✗ | $4K |
| Apr 11, 2025 | Torok Michael | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 1, 2025 | Apr 9, 2025 | Fishman Peter L. | CFO | Sell | 47.5 | -1,748 | -1.14% | ✗ | $1.1K |
| Jan 30, 2025 | Jan 31, 2025 | Ketchum Steven B | Chief Scientific Officer | Sell | 42.5 | -93,505 | -3.14% | ✗ | $58K |
| Jan 30, 2025 | Jan 31, 2025 | Berg Aaron | CEO | Sell | 42.5 | -93,505 | -2.66% | ✗ | $58K |
| Jan 31, 2025 | Jan 31, 2025 | Fishman Peter L. | CFO | Sell | 46.3 | -31,112 | -14.59% | ✗ | $19.3K |
| Jan 10, 2025 | Jan 10, 2025 | Fishman Peter L. | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 10, 2025 | Jan 10, 2025 | Provoost Jonathan | EVP, Chief Legal Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 10, 2025 | Jan 10, 2025 | Ketchum Steven B | Chief Scientific Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 31, 2024 | Fishman Peter L. | VP, Global Controller | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Aug 2, 2024 | Aug 5, 2024 | Berg Aaron | CEO | Buy | 95.0 | +160,000 | 24.79% | ✗ | $102.4K |
| Jul 31, 2024 | Aug 1, 2024 | Ketchum Steven B | Chief Scientific Officer | Sell | 47.5 | -11,763 | -1.72% | ✗ | $9.2K |
| Jul 31, 2024 | Aug 1, 2024 | Berg Aaron | CEO | Sell | 47.5 | -11,763 | -1.79% | ✗ | $9.2K |
| Jul 1, 2024 | Jul 1, 2024 | Reilly Thomas Charles | CFO | Sell | 47.5 | -8,209 | -8.01% | ✗ | $5.7K |
| Jun 20, 2024 | Jun 21, 2024 | Reilly Thomas Charles | CFO | Sell | 46.3 | -16,417 | -16.05% | ✗ | $12K |
| Apr 18, 2024 | Apr 19, 2024 | Cohen Paul | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 18, 2024 | Apr 19, 2024 | Sullivan Diane E. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 18, 2024 | Apr 19, 2024 | Sterling Louis III | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 18, 2024 | Apr 19, 2024 | O'Connor Oliver | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 18, 2024 | Apr 19, 2024 | Odysseas Kostas D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 18, 2024 | Apr 19, 2024 | Horn Keith | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 18, 2024 | Apr 19, 2024 | DiPaolo Mark | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 18, 2024 | Apr 19, 2024 | Bonfiglio Patrice Eadon | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 1, 2024 | Feb 9, 2024 | Berg Aaron | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 1, 2024 | Feb 9, 2024 | Reilly Thomas Charles | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 1, 2024 | Feb 9, 2024 | Ketchum Steven B | Chief Scientific Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2024 | Feb 2, 2024 | Berg Aaron | President | Sell | 42.5 | -40,822 | -3.18% | ✗ | $50.6K |
| Jan 31, 2024 | Feb 2, 2024 | Ketchum Steven B | Chief Scientific Officer | Sell | 42.5 | -41,187 | -3.08% | ✗ | $51.1K |
| Jan 31, 2024 | Feb 2, 2024 | Reilly Thomas Charles | CFO | Sell | 46.3 | -24,552 | -26.26% | ✗ | $30.4K |
| Jan 22, 2024 | Jan 24, 2024 | Holt Patrick | CEO | Buy | 83.8 | +14,426 | 4.81% | ✗ | $15.7K |
| Jan 10, 2024 | Jan 12, 2024 | Ketchum Steven B | Chief Scientific Officer | Sell | 46.3 | -28,270 | -4.36% | ✗ | $27.4K |
| Jan 10, 2024 | Jan 12, 2024 | Reilly Thomas Charles | CFO | Sell | 46.3 | -28,325 | -36.85% | ✗ | $27.5K |
| Jan 10, 2024 | Jan 12, 2024 | Berg Aaron | President | Sell | 46.3 | -28,214 | -4.53% | ✗ | $27.4K |
| Jan 4, 2024 | Jan 8, 2024 | Ketchum Steven B | Chief Scientific Officer | Sell | 47.5 | -7,730 | -1.28% | ✗ | $6.7K |
| Jan 4, 2024 | Jan 8, 2024 | Berg Aaron | President | Sell | 46.3 | -15,460 | -2.63% | ✗ | $13.5K |
| Dec 29, 2023 | Jan 2, 2024 | Ketchum Steven B | Chief Scientific Officer | Buy | 83.8 | +23,525 | 4.15% | ✗ | $20.5K |
| Dec 29, 2023 | Jan 2, 2024 | Berg Aaron | President | Sell | 46.3 | -23,525 | -4.05% | ✗ | $20.5K |
| Dec 12, 2023 | Dec 14, 2023 | Ketchum Steven B | Chief Scientific Officer | Sell | 36.3 | -34,131 | -5.69% | ✓ | $27K |
| Dec 1, 2023 | Dec 5, 2023 | Provoost Jonathan | EVP, Chief Legal Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 21, 2023 | Provoost Jonathan | EVP, Chief Legal Officer | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Aug 16, 2023 | Aug 16, 2023 | Holt Patrick | CEO | Buy | 97.5 | +300,000 | 31.79% | ✗ | $312.3K |
| Aug 1, 2023 | Aug 2, 2023 | Holt Patrick | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 31, 2023 | Aug 2, 2023 | Berg Aaron | President | Sell | 46.3 | -11,763 | -2.16% | ✗ | $14K |
| Jul 31, 2023 | Aug 2, 2023 | Ketchum Steven B | Chief Scientific Officer | Sell | 46.3 | -11,763 | -1.92% | ✗ | $14K |
| Jul 28, 2023 | Holt Patrick | Officer | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jul 21, 2023 | Jul 21, 2023 | Odysseas Kostas D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 21, 2023 | Jul 21, 2023 | DiPaolo Mark | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 21, 2023 | Jul 21, 2023 | Cohen Paul | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 21, 2023 | Jul 21, 2023 | Sterling Louis III | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 21, 2023 | Jul 21, 2023 | O'Connor Oliver | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 21, 2023 | Jul 21, 2023 | Horn Keith | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 21, 2023 | Jul 21, 2023 | Bonfiglio Patrice Eadon | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 21, 2023 | Jul 21, 2023 | Sullivan Diane E. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 19, 2023 | Jul 21, 2023 | Berg Aaron | President | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 19, 2023 | Jul 21, 2023 | Reilly Thomas Charles | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 19, 2023 | Jul 21, 2023 | Ketchum Steven B | Chief Scientific Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 1, 2023 | Jul 5, 2023 | Reilly Thomas Charles | CFO | Sell | 47.5 | -8,209 | -24.44% | ✗ | $9.8K |
| Jun 20, 2023 | Jun 22, 2023 | Reilly Thomas Charles | CFO | Sell | 46.3 | -16,417 | -49.25% | ✗ | $19.5K |
| Apr 27, 2023 | O'Connor Oliver | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 10, 2023 | Sullivan Diane E. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 10, 2023 | Odysseas Kostas D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 10, 2023 | Cohen Paul | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 10, 2023 | Horn Keith | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 10, 2023 | DiPaolo Mark | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 10, 2023 | Sterling Louis III | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 10, 2023 | Bonfiglio Patrice Eadon | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Feb 28, 2023 | Mar 8, 2023 | Ketchum Steven B | Chief Scientific Officer | Sell | 46.3 | -7,718 | -1.30% | ✗ | $15.7K |
| Feb 28, 2023 | Mar 8, 2023 | Berg Aaron | President | Sell | 46.3 | -7,718 | -1.49% | ✗ | $15.7K |
| Jan 10, 2023 | Feb 23, 2023 | WOLD OLSEN PER | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2023 | Feb 23, 2023 | Berg Aaron | President | Sell | 87.5 | +16,398 | 3.38% | ✗ | $76.2K |
| Feb 21, 2023 | Feb 23, 2023 | Reilly Thomas Charles | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2023 | Feb 23, 2023 | Mikhail Karim | CEO | Sell | 42.5 | -38,977 | -12.09% | ✗ | $133.9K |
| Jan 31, 2023 | Feb 23, 2023 | Ketchum Steven B | Chief Scientific Officer | Sell | 42.5 | -57,360 | -3.19% | ✗ | $51.6K |
| Jan 9, 2023 | Jan 12, 2023 | Stewart Murray | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 12, 2023 | Stewart Murray | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Dec 30, 2022 | Jan 4, 2023 | Berg Aaron | President | Sell | 46.3 | -16,361 | -3.50% | ✗ | $19.8K |
| Dec 30, 2022 | Jan 4, 2023 | Ketchum Steven B | Chief Scientific Officer | Sell | 46.3 | -16,361 | -2.92% | ✗ | $19.8K |
| Dec 30, 2022 | Jan 4, 2023 | Mikhail Karim | CEO | Sell | 47.5 | -1,270 | -1.09% | ✗ | $1.5K |
| Oct 20, 2022 | Nov 2, 2022 | Murphy Geraldine | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 20, 2022 | Nov 2, 2022 | Berger Adam Mark | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 2, 2022 | Murphy Geraldine | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |