2026Q1
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| Canaan IX L.P. | — | 3,589,554 | Oct 15, 2020 |
| Canaan Partners IX LLC | — | 3,589,554 | Oct 15, 2020 |
| Crews Craig Martin | — | 2,106,692 | Sep 26, 2018 |
| Loven Jakob | Director | 1,381,851 | Oct 3, 2018 |
| Houston John G | Director | 1,157,480 | Feb 25, 2025 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Feb 26, 2026 | Mar 2, 2026 | Loomis David K | VP, Chief Accounting Officer | Neutral | 90.0 | +12,420 | 41.83% | ✗ | - |
| Feb 26, 2026 | Mar 2, 2026 | Cacace Angela M | Chief Scientific Officer | Neutral | 90.0 | +45,000 | 30.48% | ✗ | - |
| Feb 26, 2026 | Mar 2, 2026 | Berkowitz Noah | Chief Medical Officer | Neutral | 90.0 | +45,000 | 27.45% | ✗ | - |
| Feb 26, 2026 | Mar 2, 2026 | Saik Andrew | CFO | Neutral | 90.0 | +45,000 | 28.25% | ✗ | - |
| Feb 26, 2026 | Mar 2, 2026 | Teel Randy | CEO | Neutral | 90.0 | +147,791 | 98.73% | ✗ | - |
| Feb 27, 2026 | Mar 2, 2026 | Houston John G | Director | Sell | 40.0 | -35,297 | -3.05% | ✗ | $466.2K |
| Feb 23, 2026 | Feb 25, 2026 | Loomis David K | Chief Accounting Officer | Sell | 46.3 | -1,108 | -3.60% | ✗ | $13.5K |
| Feb 23, 2026 | Feb 25, 2026 | Cacace Angela M | Chief Scientific Officer | Sell | 46.3 | -3,609 | -2.39% | ✗ | $43.9K |
| Feb 23, 2026 | Feb 25, 2026 | Teel Randy | CEO | Sell | 42.5 | -4,786 | -3.10% | ✗ | $58.2K |
| Feb 13, 2026 | Feb 18, 2026 | Teel Randy | CEO | Sell | 42.5 | -4,403 | -2.77% | ✗ | $52.4K |
| Feb 13, 2026 | Feb 18, 2026 | Saik Andrew | CFO | Sell | 42.5 | -5,134 | -3.12% | ✗ | $61K |
| Feb 13, 2026 | Feb 18, 2026 | Cacace Angela M | Chief Scientific Officer | Sell | 42.5 | -4,592 | -2.95% | ✗ | $54.6K |
| Feb 13, 2026 | Feb 18, 2026 | Berkowitz Noah | Chief Medical Officer | Sell | 42.5 | -5,685 | -3.35% | ✗ | $67.6K |
| Feb 13, 2026 | Feb 18, 2026 | Loomis David K | Chief Accounting Officer | Sell | 46.3 | -1,016 | -3.19% | ✗ | $12.1K |
| Feb 18, 2026 | Teel Randy | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Nov 7, 2025 | Nov 7, 2025 | Loomis David K | Chief Accounting Officer | Sell | 50.0 | -230 | -0.72% | ✗ | $2.3K |
| Sep 22, 2025 | Sep 24, 2025 | Morrison Briggs | Director | Buy | 95.0 | +30,000 | 65.19% | ✗ | $227K |
| Jun 25, 2025 | Jun 30, 2025 | AGARWAL SUNIL | Director | Neutral | 90.0 | +16,025 | 113.32% | ✗ | - |
| Jun 25, 2025 | Jun 27, 2025 | Smaldone Alsup Laurie | Director | Neutral | 90.0 | +16,025 | 159.93% | ✗ | - |
| Jun 25, 2025 | Jun 27, 2025 | Morrison Briggs | Director | Neutral | 90.0 | +16,025 | 53.42% | ✗ | - |
| Jun 25, 2025 | Jun 27, 2025 | YOUNG JOHN D | Director | Neutral | 90.0 | +16,025 | 159.93% | ✗ | - |
| Jun 25, 2025 | Jun 27, 2025 | Bain Linda | Director | Neutral | 90.0 | +16,025 | 159.93% | ✗ | - |
| Jun 25, 2025 | Jun 27, 2025 | Kennedy Edward Moore Jr. | Director | Neutral | 90.0 | +16,025 | 30.39% | ✗ | - |
| Jun 25, 2025 | Jun 27, 2025 | Cunningham Everett | Director | Neutral | 90.0 | +16,025 | 159.93% | ✗ | - |
| Jun 25, 2025 | Jun 27, 2025 | Norwalk Leslie V | Director | Neutral | 90.0 | +16,025 | 159.93% | ✗ | - |
| Jun 24, 2025 | Jun 24, 2025 | Saik Andrew | CFO | Sell | 46.3 | -5,700 | -3.35% | ✗ | $43.4K |
| Jun 17, 2025 | Jun 18, 2025 | Cacace Angela M | Chief Scientific Officer | Sell | 46.3 | -2,583 | -1.65% | ✗ | $19.3K |
| May 9, 2025 | May 13, 2025 | Loomis David K | Chief Accounting Officer | Neutral | 90.0 | +11,825 | 62.69% | ✗ | - |
| May 9, 2025 | May 13, 2025 | Saik Andrew | CFO | Neutral | 90.0 | +59,600 | 53.94% | ✗ | - |
| May 9, 2025 | May 13, 2025 | Cacace Angela M | Chief Scientific Officer | Neutral | 90.0 | +59,600 | 61.30% | ✗ | - |
| May 9, 2025 | May 13, 2025 | Berkowitz Noah | Chief Medical Officer | Neutral | 90.0 | +59,600 | 54.17% | ✗ | - |
| Mar 18, 2025 | Mar 19, 2025 | Berkowitz Noah | Chief Medical Officer | Sell | 42.5 | -8,658 | -7.30% | ✗ | $74.4K |
| Feb 24, 2025 | Feb 25, 2025 | Loomis David K | Chief Accounting Officer | Sell | 46.3 | -1,214 | -6.05% | ✗ | $20.3K |
| Feb 24, 2025 | Feb 25, 2025 | Cacace Angela M | Chief Scientific Officer | Sell | 42.5 | -4,207 | -4.15% | ✗ | $70.2K |
| Feb 24, 2025 | Feb 25, 2025 | Taylor Ian | President | Sell | 42.5 | -9,020 | -5.36% | ✗ | $150.8K |
| Feb 24, 2025 | Feb 25, 2025 | Houston John G | CEO | Sell | 40.0 | -31,338 | -2.64% | ✗ | $523.9K |
| Feb 13, 2025 | Feb 18, 2025 | Loomis David K | Chief Accounting Officer | Neutral | 90.0 | +10,584 | 131.64% | ✗ | - |
| Feb 13, 2025 | Feb 18, 2025 | Saik Andrew | CFO | Neutral | 90.0 | +49,092 | 79.94% | ✗ | - |
| Feb 13, 2025 | Feb 18, 2025 | Taylor Ian | Chief Scientific Officer | Neutral | 90.0 | +20,619 | 13.98% | ✗ | - |
| Feb 13, 2025 | Feb 18, 2025 | Berkowitz Noah | Chief Medical Officer | Neutral | 90.0 | +55,229 | 87.04% | ✗ | - |
| Feb 13, 2025 | Feb 18, 2025 | Cacace Angela M | Chief Scientific Officer | Neutral | 90.0 | +49,092 | 94.68% | ✗ | - |
| Feb 13, 2025 | Feb 18, 2025 | Houston John G | CEO | Neutral | 90.0 | +152,000 | 14.66% | ✗ | - |
| Nov 8, 2023 | Nov 12, 2024 | Loomis David K | Chief Accounting Officer | Sell | 46.3 | -460 | -5.41% | ✗ | $10.3K |
| Jun 24, 2024 | Jun 26, 2024 | Saik Andrew | CFO | Neutral | 90.0 | +61,409 | 100.00% | ✗ | - |
| Jun 26, 2024 | Saik Andrew | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jun 17, 2024 | Jun 18, 2024 | Cacace Angela M | Chief Scientific Officer | Neutral | 90.0 | +15,995 | 44.61% | ✗ | - |
| Jun 18, 2024 | Cacace Angela M | Chief Scientific Officer | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| May 29, 2024 | May 31, 2024 | Bain Linda | Director | Neutral | 90.0 | +5,899 | 143.14% | ✗ | - |
| May 29, 2024 | May 31, 2024 | Cunningham Everett | Director | Neutral | 90.0 | +5,899 | 143.14% | ✗ | - |
| May 29, 2024 | May 31, 2024 | Kennedy Edward Moore Jr. | Director | Neutral | 90.0 | +5,899 | 12.59% | ✗ | - |
| May 29, 2024 | May 31, 2024 | AGARWAL SUNIL | Director | Neutral | 90.0 | +5,899 | 71.57% | ✗ | - |
| May 29, 2024 | May 31, 2024 | Morrison Briggs | Director | Neutral | 90.0 | +5,899 | 24.48% | ✗ | - |
| May 29, 2024 | May 31, 2024 | YOUNG JOHN D | Director | Neutral | 90.0 | +5,899 | 143.14% | ✗ | - |
| May 29, 2024 | May 31, 2024 | Norwalk Leslie V | Director | Neutral | 90.0 | +5,899 | 143.14% | ✗ | - |
| May 29, 2024 | May 31, 2024 | Smaldone Alsup Laurie | Director | Neutral | 90.0 | +5,899 | 143.14% | ✗ | - |
| May 21, 2024 | May 23, 2024 | Teel Randy | CFO | Neutral | 90.0 | +13,300 | 28.89% | ✗ | - |
| Mar 18, 2024 | Mar 21, 2024 | Berkowitz Noah | Chief Medical Officer | Neutral | 90.0 | +63,452 | 100.00% | ✗ | - |
| Mar 21, 2024 | Berkowitz Noah | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 19, 2024 | Teel Randy | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Feb 23, 2024 | Feb 27, 2024 | Houston John G | CEO | Sell | 95.0 | +119,254 | 13.00% | ✗ | $244.5K |
| Feb 23, 2024 | Feb 27, 2024 | Cassidy Sean A | CFO | Sell | 45.0 | -1,702 | -0.93% | ✗ | $80.1K |
| Feb 23, 2024 | Feb 27, 2024 | Peck Ronald | Chief Medical Officer | Sell | 95.0 | +37,551 | 125.32% | ✗ | $79.9K |
| Feb 23, 2024 | Feb 27, 2024 | Taylor Ian | Chief Scientific Officer | Sell | 95.0 | +37,549 | 34.14% | ✗ | $80K |
| Feb 23, 2024 | Feb 27, 2024 | Loomis David K | Chief Accounting Officer | Neutral | 90.0 | +5,750 | 209.09% | ✗ | - |
| Jan 4, 2024 | Jan 8, 2024 | Taylor Ian | Chief Scientific Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Aug 11, 2023 | Aug 14, 2023 | Peck Ronald | Chief Medical Officer | Sell | 46.3 | -1,324 | -4.23% | ✗ | $32.3K |
| Jun 15, 2023 | Jun 20, 2023 | YOUNG JOHN D | Director | Neutral | 90.0 | +4,121 | 100.00% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | Smaldone Alsup Laurie | Director | Neutral | 90.0 | +4,121 | 100.00% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | Norwalk Leslie V | Director | Neutral | 90.0 | +4,121 | 100.00% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | Morrison Briggs | Director | Neutral | 90.0 | +4,121 | 20.63% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | Kennedy Edward Moore Jr. | Director | Neutral | 85.0 | +4,121 | 9.65% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | DIXON WENDY L | Director | Neutral | 90.0 | +4,121 | 82.42% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | Cunningham Everett | Director | Neutral | 90.0 | +4,121 | 100.00% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | Bain Linda | Director | Neutral | 90.0 | +4,121 | 100.00% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | AGARWAL SUNIL | Director | Neutral | 90.0 | +8,242 | 100.00% | ✗ | - |
| Jun 20, 2023 | AGARWAL SUNIL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 1, 2023 | Mar 3, 2023 | Taylor Ian | Chief Scientific Officer | Sell | 46.3 | -1,051 | -1.02% | ✗ | $31K |
| Mar 1, 2023 | Mar 3, 2023 | Houston John G | CEO | Sell | 45.0 | -5,878 | -0.64% | ✗ | $173.6K |
| Mar 1, 2023 | Mar 3, 2023 | Cassidy Sean A | CFO | Sell | 45.0 | -1,745 | -0.94% | ✗ | $51.5K |
| Feb 22, 2023 | Feb 24, 2023 | Cassidy Sean A | CFO | Neutral | 90.0 | +19,125 | 11.85% | ✗ | - |
| Feb 22, 2023 | Feb 24, 2023 | Peck Ronald | Chief Medical Officer | Neutral | 90.0 | +19,125 | 234.55% | ✗ | - |
| Feb 22, 2023 | Feb 24, 2023 | Houston John G | CEO | Neutral | 85.0 | +61,975 | 7.34% | ✗ | - |
| Feb 22, 2023 | Feb 24, 2023 | Taylor Ian | Chief Scientific Officer | Neutral | 90.0 | +19,125 | 23.62% | ✗ | - |
| Dec 23, 2022 | Loomis David K | Chief Accounting Officer | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Dec 15, 2022 | Dec 19, 2022 | Cunningham Everett | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 19, 2022 | Cunningham Everett | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Aug 18, 2022 | Aug 22, 2022 | YOUNG JOHN D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Aug 22, 2022 | YOUNG JOHN D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Aug 12, 2022 | Aug 16, 2022 | Peck Ronald | Chief Medical Officer | Sell | 42.5 | -1,258 | -13.37% | ✗ | $69K |
| Aug 12, 2022 | Aug 16, 2022 | Peck Ronald | Chief Medical Officer | Sell | 42.5 | -1,258 | -13.37% | ✗ | $86.8K |
| Jun 16, 2022 | Jun 21, 2022 | DIXON WENDY L | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 16, 2022 | Jun 21, 2022 | SHANNON TIMOTHY M | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 16, 2022 | Jun 21, 2022 | Ratcliffe Liam | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 16, 2022 | Jun 21, 2022 | Kennedy Edward Moore Jr. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 16, 2022 | Jun 21, 2022 | Smaldone Alsup Laurie | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 16, 2022 | Jun 21, 2022 | Bain Linda | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 16, 2022 | Jun 21, 2022 | Margus Bradley Albert | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 16, 2022 | Jun 21, 2022 | Morrison Briggs | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 16, 2022 | Jun 21, 2022 | Norwalk Leslie V | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 14, 2022 | Apr 18, 2022 | Morrison Briggs | Director | Sell | 5.0 | -20,960 | -51.20% | ✓ | $1.4M |