89bio, Inc. (ETNB)

Latest Insider Confidence Score

2025Q4

49.8
Bearish

Company insider confidence (by quarter)

2019Q4 2025Q4

Largest shareholders

Insider Role (last 12 mo) Shares held Filed at
Naschitz Anat Director 1,864,721 Sep 23, 2020
Orbimed Advisors Llc 10% Owner 1,829,436 Jan 27, 2022
OrbiMed Advisors Israel II Ltd 10% Owner 1,829,436 Jan 27, 2022
OrbiMed Israel GP II, L.P. 10% Owner 1,829,436 Jan 27, 2022
OrbiMed Capital GP VI LLC 10% Owner 1,829,436 Jan 27, 2022

Recent buy/sell transactions

Exec date Filing date Insider Role Signal Confidence Shares % of shares Under plan? Amount (USD)
Oct 30, 2025 Nov 3, 2025 RA CAPITAL MANAGEMENT, L.P. Director Neutral 47.5 -19,889,683 -100.00% ✗ -
Oct 30, 2025 Oct 30, 2025 LAPORTE KATHLEEN Director Neutral 52.5 - 0.00% ✗ -
Oct 30, 2025 Oct 30, 2025 Hayden Michael R Director Neutral 47.5 -246,420 -100.00% ✗ -
Oct 30, 2025 Oct 30, 2025 Martins Ryan CFO Neutral 47.5 -339,295 -100.00% ✗ -
Oct 30, 2025 Oct 30, 2025 Altschuler Steven Director Neutral 52.5 - 0.00% ✗ -
Oct 30, 2025 Oct 30, 2025 PALEKAR ROHAN CEO Neutral 47.5 -809,273 -100.00% ✗ -
Oct 30, 2025 Oct 30, 2025 McWherter Charles Director Neutral 47.5 -25,000 -100.00% ✗ -
Oct 30, 2025 Oct 30, 2025 Atkinson Edward Morrow III Director Neutral 52.5 - 0.00% ✗ -
Oct 30, 2025 Oct 30, 2025 Zoth Lota S. Director Neutral 52.5 - 0.00% ✗ -
Oct 30, 2025 Oct 30, 2025 Le-Nguyen Quoc Officer Neutral 47.5 -315,378 -100.00% ✗ -
Oct 30, 2025 Oct 30, 2025 Babler Martin Director Neutral 52.5 - 0.00% ✗ -
Oct 30, 2025 Oct 30, 2025 DiRocco Derek Director Neutral 52.5 - 0.00% ✗ -
Oct 30, 2025 Oct 30, 2025 Sarena Francis Willard COO Neutral 47.5 -75,310 -100.00% ✗ -
Oct 30, 2025 Oct 30, 2025 Mansbach Harry H Chief Medical Officer Neutral 47.5 -302,656 -100.00% ✗ -
Oct 22, 2025 Oct 23, 2025 Martins Ryan CFO Neutral 52.5 - 0.00% ✗ -
Aug 1, 2025 Aug 5, 2025 Le-Nguyen Quoc Officer Sell 42.5 -8,202 -2.53% ✗ $75.1K
Aug 1, 2025 Aug 5, 2025 Mansbach Harry H Chief Medical Officer Sell 42.5 -7,680 -2.47% ✗ $70.3K
Aug 1, 2025 Aug 5, 2025 Martins Ryan CFO Sell 42.5 -7,680 -2.94% ✗ $70.3K
Aug 1, 2025 Aug 5, 2025 Sarena Francis Willard COO Sell 42.5 -6,185 -7.69% ✗ $58.2K
Aug 1, 2025 Aug 5, 2025 PALEKAR ROHAN CEO Sell 40.0 -55,836 -6.46% ✗ $511.5K
Jul 15, 2025 Jul 17, 2025 Le-Nguyen Quoc Officer Sell 37.5 -10,461 -3.13% ✓ $115.3K
Jun 12, 2025 Jun 13, 2025 Martins Ryan CFO Sell 42.5 -8,498 -3.15% ✗ $81.8K
Jun 12, 2025 Jun 13, 2025 Mansbach Harry H Chief Medical Officer Sell 42.5 -8,498 -2.67% ✗ $81.8K
Jun 12, 2025 Jun 13, 2025 Le-Nguyen Quoc Officer Sell 42.5 -9,032 -2.63% ✗ $86.9K
Apr 15, 2025 Apr 17, 2025 Le-Nguyen Quoc Officer Sell 37.5 -15,329 -4.28% ✓ $91.2K
Dec 12, 2024 Feb 19, 2025 Le-Nguyen Quoc Officer Sell 83.8 +13,700 3.97% ✗ $11.1K
Feb 17, 2025 Feb 19, 2025 PALEKAR ROHAN CEO Sell 51.3 -3,249 -0.38% ✗ $34.3K
Feb 17, 2025 Feb 19, 2025 Martins Ryan CFO Sell 52.5 -780 -0.29% ✗ $8.2K
Feb 17, 2025 Feb 19, 2025 Mansbach Harry H Chief Medical Officer Sell 51.3 -1,050 -0.33% ✗ $11.1K
Feb 9, 2025 Feb 11, 2025 PALEKAR ROHAN CEO Sell 42.5 -8,946 -1.02% ✗ $102.1K
Feb 9, 2025 Feb 11, 2025 Martins Ryan CFO Sell 46.3 -3,828 -1.40% ✗ $43.7K
Feb 9, 2025 Feb 11, 2025 Le-Nguyen Quoc Officer Sell 46.3 -3,793 -1.09% ✗ $43.3K
Feb 9, 2025 Feb 11, 2025 Mansbach Harry H Chief Medical Officer Sell 46.3 -3,817 -1.18% ✗ $43.6K
Feb 3, 2025 Feb 5, 2025 RA CAPITAL MANAGEMENT, L.P. Director Neutral 52.5 - 0.00% ✗ -
Feb 3, 2025 Feb 5, 2025 DiRocco Derek Director Neutral 52.5 - 0.00% ✗ -
Feb 3, 2025 Feb 5, 2025 Zoth Lota S. Director Neutral 52.5 - 0.00% ✗ -
Feb 3, 2025 Feb 5, 2025 Babler Martin Director Neutral 52.5 - 0.00% ✗ -
Feb 3, 2025 Feb 5, 2025 Altschuler Steven Director Neutral 52.5 - 0.00% ✗ -
Feb 3, 2025 Feb 5, 2025 LAPORTE KATHLEEN Director Neutral 52.5 - 0.00% ✗ -
Feb 3, 2025 Feb 5, 2025 Hayden Michael R Director Neutral 52.5 - 0.00% ✗ -
Feb 3, 2025 Feb 5, 2025 McWherter Charles Director Neutral 52.5 - 0.00% ✗ -
Feb 3, 2025 Feb 5, 2025 Atkinson Edward Morrow III Director Neutral 52.5 - 0.00% ✗ -
Feb 1, 2025 Feb 4, 2025 Martins Ryan CFO Sell 91.3 +76,662 38.79% ✗ $32K
Feb 1, 2025 Feb 4, 2025 Le-Nguyen Quoc Officer Sell 91.3 +76,662 28.20% ✗ $32K
Feb 1, 2025 Feb 4, 2025 PALEKAR ROHAN CEO Sell 95.0 +402,402 85.39% ✗ $92.1K
Feb 1, 2025 Feb 4, 2025 Mansbach Harry H Chief Medical Officer Sell 91.3 +76,662 31.03% ✗ $32K
Feb 1, 2025 Feb 4, 2025 Sarena Francis Willard COO Neutral 90.0 +53,750 215.00% ✗ -
Jan 30, 2025 Feb 3, 2025 RA CAPITAL MANAGEMENT, L.P. Director Buy 100.0 +5,714,285 41.29% ✗ $50M
Jan 21, 2025 Jan 23, 2025 McWherter Charles Director Buy 95.0 +15,000 150.00% ✗ $99.9K
Jan 15, 2025 Jan 17, 2025 Le-Nguyen Quoc Officer Sell 37.5 -10,963 -3.88% ✓ $71.1K
Dec 12, 2024 Dec 16, 2024 Mansbach Harry H Chief Medical Officer Neutral 27.5 -95,000 -27.77% ✗ -
Dec 12, 2024 Dec 16, 2024 Le-Nguyen Quoc Officer Neutral 27.5 -95,000 -25.15% ✗ -
Dec 12, 2024 Dec 16, 2024 Martins Ryan CFO Neutral 27.5 -95,000 -32.47% ✗ -
Dec 6, 2024 Dec 10, 2024 PALEKAR ROHAN CEO Buy 78.8 +5,000 1.07% ✗ $39.5K
Dec 5, 2024 Dec 9, 2024 McWherter Charles Director Buy 95.0 +10,000 100.00% ✗ $80K
Nov 22, 2024 Nov 25, 2024 PALEKAR ROHAN CEO Buy 82.5 +10,000 2.19% ✗ $83.5K
Nov 14, 2024 Nov 18, 2024 RA CAPITAL MANAGEMENT, L.P. Director Neutral 52.5 - 0.00% ✗ -
Oct 30, 2024 Nov 1, 2024 Le-Nguyen Quoc Officer Sell 25.0 -27,955 -12.96% ✓ $227K
Sep 9, 2024 Sep 10, 2024 Mansbach Harry H Chief Medical Officer Sell 46.3 -5,352 -3.40% ✗ $45.3K
Sep 9, 2024 Sep 10, 2024 Martins Ryan CFO Sell 46.3 -3,212 -3.03% ✗ $27.2K
Sep 9, 2024 Sep 10, 2024 Le-Nguyen Quoc Officer Sell 46.3 -5,352 -2.42% ✗ $45.3K
Aug 17, 2024 Aug 19, 2024 Mansbach Harry H Chief Medical Officer Sell 50.0 -1,046 -0.66% ✗ $8.4K
Aug 17, 2024 Aug 19, 2024 PALEKAR ROHAN CEO Sell 48.8 -4,601 -1.00% ✗ $37K
Aug 17, 2024 Aug 19, 2024 Martins Ryan CFO Sell 50.0 -777 -0.73% ✗ $6.2K
Aug 17, 2024 Aug 19, 2024 Le-Nguyen Quoc Officer Sell 52.5 -1,046 -0.47% ✗ $8.4K
Aug 5, 2024 Aug 7, 2024 McWherter Charles Director Neutral 52.5 - 0.00% ✗ -
Aug 5, 2024 Aug 7, 2024 Sarena Francis Willard COO Neutral 90.0 +25,000 100.00% ✗ -
Aug 7, 2024 Sarena Francis Willard COO Neutral 52.5 - 0.00% ✗ -
Aug 7, 2024 McWherter Charles Director Neutral 52.5 - 0.00% ✗ -
May 2, 2024 May 3, 2024 Babler Martin Director Neutral 52.5 - 0.00% ✗ -
Apr 23, 2024 Babler Martin Director Neutral 52.5 - 0.00% ✗ -
Apr 11, 2024 Apr 15, 2024 RA CAPITAL MANAGEMENT, L.P. Director Neutral 52.5 - 0.00% ✗ -
Apr 1, 2024 Apr 3, 2024 PALEKAR ROHAN CEO Sell 22.5 -52,718 -10.30% ✓ $575.2K
Mar 4, 2024 Mar 6, 2024 RA CAPITAL MANAGEMENT, L.P. Director Buy 100.0 +1,350,000 12.18% ✗ $20.7M
Feb 26, 2024 Feb 28, 2024 PALEKAR ROHAN CEO Sell 51.3 -4,477 -0.91% ✓ $48.2K
Feb 17, 2024 Feb 23, 2024 Martins Ryan CFO Sell 50.0 -778 -0.72% ✗ $7.6K
Feb 17, 2024 Feb 23, 2024 PALEKAR ROHAN CEO Sell 48.8 -4,602 -0.93% ✗ $44.8K
Feb 17, 2024 Feb 23, 2024 Le-Nguyen Quoc Officer Sell 51.3 -1,046 -0.47% ✗ $10.2K
Feb 17, 2024 Feb 23, 2024 Mansbach Harry H Chief Medical Officer Sell 48.8 -1,046 -0.66% ✗ $10.2K
Feb 9, 2024 Feb 13, 2024 Martins Ryan CFO Sell 46.3 -3,568 -3.22% ✗ $30.1K
Feb 9, 2024 Feb 13, 2024 Mansbach Harry H Chief Medical Officer Sell 46.3 -3,568 -2.19% ✗ $30.1K
Feb 9, 2024 Feb 13, 2024 Le-Nguyen Quoc Officer Sell 46.3 -3,568 -1.57% ✗ $30.1K
Feb 9, 2024 Feb 13, 2024 PALEKAR ROHAN CEO Sell 42.5 -12,670 -2.57% ✗ $107.1K
Feb 1, 2024 Feb 5, 2024 Mansbach Harry H Chief Medical Officer Sell 91.3 +47,560 41.18% ✗ $11.7K
Feb 1, 2024 Feb 5, 2024 Le-Nguyen Quoc Officer Sell 91.3 +47,560 26.54% ✗ $11.7K
Feb 1, 2024 Feb 5, 2024 Hayden Michael R Director Neutral 52.5 - 0.00% ✗ -
Feb 1, 2024 Feb 5, 2024 DiRocco Derek Director Neutral 52.5 - 0.00% ✗ -
Feb 1, 2024 Feb 5, 2024 PALEKAR ROHAN CEO Sell 91.3 +144,932 41.56% ✗ $49.7K
Feb 1, 2024 Feb 5, 2024 Atkinson Edward Morrow III Director Neutral 52.5 - 0.00% ✗ -
Feb 1, 2024 Feb 5, 2024 LAPORTE KATHLEEN Director Neutral 52.5 - 0.00% ✗ -
Feb 1, 2024 Feb 5, 2024 Altschuler Steven Director Neutral 52.5 - 0.00% ✗ -
Feb 1, 2024 Feb 5, 2024 Zoth Lota S. Director Neutral 52.5 - 0.00% ✗ -
Feb 1, 2024 Feb 5, 2024 Martins Ryan CFO Sell 90.0 +47,858 75.85% ✗ $8.7K
Jan 5, 2024 Jan 8, 2024 Mansbach Harry H Chief Medical Officer Sell 95.0 +15,329 15.30% ✗ $111.5K
Jan 5, 2024 Jan 8, 2024 Martins Ryan CFO Sell 95.0 +8,876 16.37% ✗ $70.6K
Jan 5, 2024 Jan 8, 2024 Le-Nguyen Quoc Officer Sell 90.0 +15,329 9.35% ✗ $111.5K
Jan 5, 2024 Jan 8, 2024 PALEKAR ROHAN CEO Sell 97.5 +47,489 15.77% ✗ $317.2K
Dec 29, 2023 Jan 3, 2024 PALEKAR ROHAN CEO Sell 22.5 -50,000 -14.24% ✓ $560K
Dec 11, 2023 Dec 13, 2023 RA CAPITAL MANAGEMENT, L.P. Director Neutral 52.5 - 0.00% ✗ -
Sep 9, 2023 Sep 12, 2023 Mansbach Harry H Chief Medical Officer Sell 42.5 -3,821 -3.67% ✗ $63.5K