2025Q4
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| Bvf Partners L P/Il | — | 7,590,690 | Feb 27, 2026 |
| Biotechnology Value Fund L P | — | 7,590,690 | Feb 27, 2026 |
| Bvf I Gp Llc | — | 7,590,690 | Feb 27, 2026 |
| Biotechnology Value Fund II Lp | — | 7,590,690 | Feb 27, 2026 |
| Bvf II Gp Llc | — | 7,590,690 | Feb 27, 2026 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Feb 27, 2026 | BVF PARTNERS L P/IL | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Feb 27, 2026 | Nagel Robert Thorvald | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jul 16, 2025 | Jul 18, 2025 | Whaley Glenn | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 16, 2025 | Jul 18, 2025 | Nash Duane | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 16, 2025 | Jul 18, 2025 | Vitt Daniel | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 16, 2025 | Jul 18, 2025 | Muehler Andreas | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 16, 2025 | Jul 18, 2025 | Tardio Jason | COO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 20, 2025 | Tardio Jason | COO | Buy | 90.0 | +12,512 | 100.00% | ✗ | $9.9K |
| Jun 5, 2025 | Jun 20, 2025 | Whaley Glenn | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 4, 2025 | Jun 20, 2025 | Vitt Daniel | CEO | Buy | 83.8 | +15,000 | 3.98% | ✗ | $11.6K |
| Jun 5, 2025 | Jun 20, 2025 | Nash Duane | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 20, 2025 | Muehler Andreas | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 13, 2025 | Jun 16, 2025 | Nash Duane | Chair | Buy | 91.3 | +20,000 | 124.75% | ✗ | $16.7K |
| Jun 5, 2025 | Jun 9, 2025 | HOWSON TAMAR D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | Skerjanec Simona | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | Rudick Richard Alan | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | Toernsen Monika Maria | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | Tardio Jason | COO | Buy | 90.0 | +12,512 | 100.00% | ✗ | $9.9K |
| Jun 5, 2025 | Jun 9, 2025 | Neermann Joerg | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | Whaley Glenn | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | Nash Duane | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | PHILLIPS BARCLAY A | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2025 | Jun 9, 2025 | Muehler Andreas | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 4, 2025 | Jun 6, 2025 | Vitt Daniel | CEO | Buy | 83.8 | +15,000 | 3.98% | ✗ | $11.6K |
| Jun 4, 2025 | Jun 5, 2025 | Neermann Joerg | Director | Buy | 95.0 | +100,000 | 100.00% | ✗ | $76.7K |
| May 30, 2025 | Jun 4, 2025 | Whaley Glenn | CFO | Buy | 91.3 | +70,000 | 274.40% | ✗ | $32.1K |
| Jun 3, 2025 | Jun 4, 2025 | Rudick Richard Alan | Director | Buy | 95.0 | +143,075 | 163.89% | ✗ | $100K |
| Dec 4, 2024 | Dec 9, 2024 | Nash Duane | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 4, 2024 | Dec 6, 2024 | Nash Duane | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 4, 2024 | Dec 6, 2024 | Muehler Andreas | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 4, 2024 | Dec 6, 2024 | Tardio Jason | COO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 4, 2024 | Dec 6, 2024 | Vitt Daniel | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 4, 2024 | Dec 6, 2024 | Whaley Glenn | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 12, 2024 | Nov 13, 2024 | Rudick Richard Alan | Director | Buy | 95.0 | +87,300 | 100.00% | ✗ | $100.4K |
| Jul 22, 2024 | Jul 24, 2024 | Skerjanec Simona | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 24, 2024 | Skerjanec Simona | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jul 12, 2024 | Jul 12, 2024 | Tardio Jason | COO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 12, 2024 | Tardio Jason | COO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jun 11, 2024 | Jun 12, 2024 | Neermann Joerg | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 11, 2024 | Jun 12, 2024 | PHILLIPS BARCLAY A | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 11, 2024 | Jun 12, 2024 | Rudick Richard Alan | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 11, 2024 | Jun 12, 2024 | Toernsen Monika Maria | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 11, 2024 | Jun 12, 2024 | HOWSON TAMAR D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 4, 2024 | Mar 6, 2024 | HOWSON TAMAR D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 4, 2024 | Mar 6, 2024 | Nash Duane | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 4, 2024 | Mar 6, 2024 | PHILLIPS BARCLAY A | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 4, 2024 | Mar 6, 2024 | Vitt Daniel | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 4, 2024 | Mar 6, 2024 | Muehler Andreas | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 4, 2024 | Mar 6, 2024 | Whaley Glenn | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 4, 2024 | Mar 6, 2024 | Neermann Joerg | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 4, 2024 | Mar 6, 2024 | Toernsen Monika Maria | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 26, 2024 | Feb 28, 2024 | Vitt Daniel | CEO | Buy | 83.8 | +14,000 | 3.71% | ✗ | $18.3K |
| Jan 17, 2024 | Jan 19, 2024 | Nash Duane | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 17, 2024 | Jan 19, 2024 | Vitt Daniel | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 17, 2024 | Jan 19, 2024 | Muehler Andreas | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 17, 2024 | Jan 19, 2024 | Whaley Glenn | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 28, 2023 | Jun 29, 2023 | HOWSON TAMAR D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 28, 2023 | Jun 29, 2023 | PHILLIPS BARCLAY A | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 28, 2023 | Jun 29, 2023 | Rudick Richard Alan | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 28, 2023 | Jun 29, 2023 | Neermann Joerg | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 28, 2023 | Jun 29, 2023 | Toernsen Monika Maria | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 15, 2023 | May 16, 2023 | Whaley Glenn | CFO | Buy | 90.0 | +5,000 | 24.38% | ✗ | $8.8K |
| Apr 26, 2023 | Apr 27, 2023 | Rudick Richard Alan | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 27, 2023 | Rudick Richard Alan | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jan 2, 2023 | Jan 6, 2023 | Muehler Andreas | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 2, 2023 | Jan 6, 2023 | Nash Duane | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 2, 2023 | Jan 6, 2023 | Whaley Glenn | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 2, 2023 | Jan 6, 2023 | Vitt Daniel | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 13, 2022 | Dec 15, 2022 | Neermann Joerg | Director | Buy | 95.0 | +82,000 | 455.56% | ✗ | $102.6K |
| Nov 23, 2022 | Nov 25, 2022 | Neermann Joerg | Director | Buy | 91.3 | +18,000 | 100.00% | ✗ | $25K |
| Nov 22, 2022 | Nov 23, 2022 | Vitt Daniel | CEO | Buy | 78.8 | +8,000 | 2.17% | ✗ | $10.8K |
| Nov 7, 2022 | Nov 8, 2022 | Whaley Glenn | CFO | Buy | 90.0 | +5,000 | 32.24% | ✗ | $7.5K |
| Jul 8, 2022 | Jul 11, 2022 | Toernsen Monika Maria | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 11, 2022 | Toernsen Monika Maria | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jun 15, 2022 | Jun 17, 2022 | Nash Duane | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 15, 2022 | Jun 17, 2022 | Muehler Andreas | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 15, 2022 | Jun 17, 2022 | PHILLIPS BARCLAY A | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 15, 2022 | Jun 17, 2022 | Ossipow Vincent | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 15, 2022 | Jun 17, 2022 | Neermann Joerg | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 15, 2022 | Jun 17, 2022 | Whaley Glenn | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 15, 2022 | Jun 17, 2022 | Vitt Daniel | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 15, 2022 | Jun 17, 2022 | HOWSON TAMAR D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 15, 2022 | Jun 17, 2022 | van den Bossche Jan | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 3, 2022 | Jun 6, 2022 | Vitt Daniel | CEO | Buy | 78.8 | +5,000 | 1.37% | ✗ | $15.5K |
| Jun 3, 2022 | Jun 6, 2022 | Whaley Glenn | CFO | Buy | 91.3 | +3,500 | 38.60% | ✗ | $10.7K |
| May 12, 2022 | May 16, 2022 | Muehler Andreas | Chief Medical Officer | Buy | 78.8 | +3,500 | 1.19% | ✗ | $17.9K |
| May 12, 2022 | May 13, 2022 | Whaley Glenn | CFO | Buy | 91.3 | +3,000 | 49.44% | ✗ | $15.2K |
| May 12, 2022 | May 13, 2022 | Nash Duane | Chair | Buy | 95.0 | +4,000 | 33.24% | ✗ | $50.3K |
| Mar 10, 2022 | Mar 11, 2022 | Nash Duane | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 10, 2022 | Mar 11, 2022 | Whaley Glenn | PAO and PFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 3, 2022 | Jan 6, 2022 | Vitt Daniel | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 3, 2022 | Jan 6, 2022 | Muehler Andreas | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 3, 2022 | Jan 6, 2022 | Whaley Glenn | PFO and PAO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 8, 2021 | Jan 3, 2022 | Nash Duane | Chair | Neutral | 27.5 | -3,000 | -19.96% | ✗ | - |
| Aug 10, 2021 | Aug 11, 2021 | Whaley Glenn | PFO and PAO | Buy | 91.3 | +1,500 | 75.00% | ✗ | $14.8K |
| Aug 10, 2021 | Aug 11, 2021 | Vitt Daniel | CEO | Buy | 60.0 | +1,000 | 0.28% | ✗ | $9.6K |
| Aug 10, 2021 | Aug 11, 2021 | Nash Duane | Chair | Buy | 85.0 | +1,000 | 7.13% | ✗ | $9.8K |
| Jun 10, 2021 | Jun 14, 2021 | Nash Duane | Chair | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 10, 2021 | Jun 14, 2021 | Ossipow Vincent | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 10, 2021 | Jun 14, 2021 | HOWSON TAMAR D | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |