2026Q1
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| Demopulos Gregory A MD | CEO | 123,945 | Oct 15, 2025 |
| Jacobsen Michael A | VP FINANCE AND CAO | 100,000 | Apr 29, 2024 |
| Cancelmo Peter B | — | 100,000 | Apr 29, 2024 |
| Borges David J. | VP, Finance & CAO | 30,000 | Jul 3, 2024 |
| Shah Rajiv | — | 15,000 | Jun 7, 2024 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Feb 18, 2026 | Feb 20, 2026 | Demopulos Gregory A MD | CEO | Sell | 17.5 | -357,678 | -14.02% | ✗ | $4.3M |
| Jan 12, 2026 | Jan 14, 2026 | Borges David J. | VP, Finance & CAO | Sell | 20.0 | -60,000 | -100.00% | ✗ | $750.9K |
| Oct 13, 2025 | Oct 15, 2025 | Demopulos Gregory A MD | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 30, 2025 | Jul 1, 2025 | Demopulos Gregory A MD | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 30, 2025 | Jul 1, 2025 | Cancelmo Peter B | VP, General Counsel | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 30, 2025 | Jul 1, 2025 | Borges David J. | VP, Finance & CAO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 27, 2025 | Jul 1, 2025 | Shah Rajiv | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 27, 2025 | Jul 1, 2025 | Perkinson Diana T. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 27, 2025 | Jul 1, 2025 | Hood Leroy E. MD PhD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 27, 2025 | Jul 1, 2025 | HANISH ARNOLD C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 27, 2025 | Jul 1, 2025 | Demopulos Peter A MD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 27, 2025 | Jul 1, 2025 | Cable Thomas J. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 27, 2025 | Jul 1, 2025 | Bumol Thomas F. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 3, 2024 | Borges David J. | VP, Finance & CAO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jun 6, 2024 | Jun 7, 2024 | Shah Rajiv | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 6, 2024 | Jun 7, 2024 | Perkinson Diana T. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 6, 2024 | Jun 7, 2024 | Hood Leroy E. MD PhD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 6, 2024 | Jun 7, 2024 | HANISH ARNOLD C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 6, 2024 | Jun 7, 2024 | Demopulos Peter A MD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 6, 2024 | Jun 7, 2024 | Cable Thomas J. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 6, 2024 | Jun 7, 2024 | Bumol Thomas F. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 25, 2024 | Apr 29, 2024 | Demopulos Gregory A MD | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 25, 2024 | Apr 29, 2024 | JACOBSEN MICHAEL A | VP, Finance & CAO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 25, 2024 | Apr 29, 2024 | Cancelmo Peter B | VP, General Counsel | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Nov 17, 2023 | Nov 21, 2023 | Demopulos Gregory A MD | CEO | Buy | 68.8 | +15,000 | 0.70% | ✗ | $25.2K |
| Nov 15, 2023 | Nov 17, 2023 | Demopulos Peter A MD | Director | Buy | 83.8 | +10,000 | 2.76% | ✗ | $15.3K |
| Nov 13, 2023 | Nov 15, 2023 | Demopulos Gregory A MD | CEO | Neutral | 82.5 | +62,500 | 3.01% | ✗ | - |
| Sep 22, 2023 | Sep 27, 2023 | Demopulos Gregory A MD | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 22, 2023 | Sep 27, 2023 | JACOBSEN MICHAEL A | VP, Finance & CAO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 22, 2023 | Sep 27, 2023 | Cancelmo Peter B | VP, General Counsel | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 12, 2023 | Sep 14, 2023 | Bumol Thomas F. | Director | Neutral | 90.0 | +10,000 | 100.00% | ✗ | - |
| Jun 23, 2023 | Jun 27, 2023 | HANISH ARNOLD C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 23, 2023 | Jun 27, 2023 | Hood Leroy E. MD PhD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 23, 2023 | Jun 27, 2023 | Demopulos Peter A MD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 23, 2023 | Jun 27, 2023 | Shah Rajiv | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 23, 2023 | Jun 27, 2023 | Bumol Thomas F. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 23, 2023 | Jun 27, 2023 | Cable Thomas J. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 22, 2023 | May 23, 2023 | HANISH ARNOLD C | Director | Sell | 26.3 | -5,000 | -28.74% | ✗ | $32.3K |
| May 22, 2023 | May 23, 2023 | Cable Thomas J. | Director | Sell | 26.3 | -5,000 | -12.48% | ✗ | $32.7K |
| May 12, 2023 | May 16, 2023 | Perkinson Diana T. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 16, 2023 | Perkinson Diana T. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Sep 21, 2022 | Sep 23, 2022 | Cable Thomas J. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2022 | Sep 23, 2022 | Bumol Thomas F. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2022 | Sep 23, 2022 | Shah Rajiv | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2022 | Sep 23, 2022 | Demopulos Peter A MD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2022 | Sep 23, 2022 | Hood Leroy E. MD PhD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2022 | Sep 23, 2022 | Zumwalt Kurt | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2022 | Sep 23, 2022 | HANISH ARNOLD C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2022 | Sep 23, 2022 | Demopulos Gregory A MD | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2022 | Sep 23, 2022 | JACOBSEN MICHAEL A | VP FINANCE AND CAO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 21, 2022 | Sep 23, 2022 | Cancelmo Peter B | VP, GENERAL COUNSEL | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 17, 2022 | Jun 22, 2022 | Zumwalt Kurt | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 17, 2022 | Jun 22, 2022 | Shah Rajiv | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 17, 2022 | Jun 22, 2022 | Demopulos Peter A MD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 17, 2022 | Jun 22, 2022 | Hood Leroy E. MD PhD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 17, 2022 | Jun 22, 2022 | HANISH ARNOLD C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 17, 2022 | Jun 22, 2022 | Cable Thomas J. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 17, 2022 | Jun 22, 2022 | Bumol Thomas F. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 11, 2021 | Feb 14, 2022 | Zumwalt Kurt | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 11, 2021 | Feb 14, 2022 | Cable Thomas J. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 11, 2021 | Feb 14, 2022 | HANISH ARNOLD C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 11, 2021 | Feb 14, 2022 | Hood Leroy E. MD PhD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 11, 2021 | Feb 14, 2022 | Demopulos Peter A MD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 11, 2021 | Feb 14, 2022 | Shah Rajiv | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 11, 2021 | Feb 14, 2022 | Bumol Thomas F. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 11, 2021 | Feb 14, 2022 | Aspiri Ray | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 8, 2021 | Sep 9, 2021 | HANISH ARNOLD C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 2, 2021 | Jul 6, 2021 | Cancelmo Peter B | VP, GEN. COUNSEL & CORP. SEC. | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 2, 2021 | Jul 6, 2021 | JACOBSEN MICHAEL A | VP FINANCE AND CAO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 2, 2021 | Jul 6, 2021 | Demopulos Gregory A MD | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 15, 2021 | Jun 17, 2021 | Demopulos Gregory A MD | CEO | Sell | 40.0 | -73,713 | -1.79% | ✓ | $1.1M |
| May 19, 2021 | May 21, 2021 | Demopulos Gregory A MD | CEO | Sell | 40.0 | -73,713 | -1.79% | ✓ | $1.2M |
| Apr 7, 2021 | Apr 8, 2021 | Demopulos Gregory A MD | CEO | Sell | 40.0 | -72,613 | -1.76% | ✓ | $1.3M |
| Feb 22, 2021 | Feb 23, 2021 | Demopulos Peter A MD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 19, 2021 | Feb 23, 2021 | JACOBSEN MICHAEL A | VP FINANCE AND CAO | Sell | 7.5 | -18,100 | -39.26% | ✓ | $415K |
| Feb 12, 2021 | Feb 17, 2021 | Hood Leroy E. MD PhD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 10, 2021 | Feb 12, 2021 | JACOBSEN MICHAEL A | VP FINANCE AND CAO | Sell | 28.8 | -1,900 | -11.95% | ✓ | $42.7K |
| Jan 19, 2021 | Jan 21, 2021 | JACOBSEN MICHAEL A | VP FINANCE AND CAO | Sell | 10.0 | -9,500 | -70.37% | ✓ | $189.5K |
| Jan 13, 2021 | Jan 15, 2021 | Cable Thomas J. | Director | Sell | 25.0 | -5,000 | -12.48% | ✓ | $84.9K |
| Oct 26, 2020 | Oct 28, 2020 | Cancelmo Peter B | VP, GEN. COUNSEL & CORP. SEC. | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2020 | Jun 9, 2020 | Cable Thomas J. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2020 | Jun 9, 2020 | Demopulos Peter A MD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2020 | Jun 9, 2020 | Hood Leroy E. MD PhD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2020 | Jun 9, 2020 | Aspiri Ray | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2020 | Jun 9, 2020 | Shah Rajiv | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2020 | Jun 9, 2020 | Bumol Thomas F. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 5, 2020 | Jun 9, 2020 | HANISH ARNOLD C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 13, 2020 | May 15, 2020 | Cable Thomas J. | Director | Sell | 25.0 | -5,000 | -12.48% | ✓ | $72K |
| Mar 13, 2020 | Mar 17, 2020 | Hood Leroy E. MD PhD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 1, 2020 | Mar 3, 2020 | Demopulos Gregory A MD | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 1, 2020 | Mar 3, 2020 | JACOBSEN MICHAEL A | VP FINANCE AND CAO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 1, 2020 | Mar 3, 2020 | Cancelmo Peter B | VP, GEN. COUNSEL & CORP. SEC. | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 10, 2020 | Feb 12, 2020 | Zumwalt Kurt | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Feb 12, 2020 | Zumwalt Kurt | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Dec 14, 2019 | Dec 17, 2019 | Hood Leroy E. MD PhD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 14, 2019 | Dec 17, 2019 | Demopulos Peter A MD | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 3, 2019 | Dec 5, 2019 | Cable Thomas J. | Director | Sell | 15.0 | -10,000 | -22.19% | ✓ | $144.1K |
| Oct 14, 2019 | Oct 16, 2019 | Cable Thomas J. | Director | Sell | 25.0 | -5,000 | -12.48% | ✓ | $75.6K |
| Jun 10, 2019 | Jun 11, 2019 | Cancelmo Peter B | Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 11, 2019 | Cancelmo Peter B | Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |