2026Q1
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| Perceptive Advisors Llc | 10% Owner | 1,800,000 | Jan 26, 2021 |
| Perceptive Life Sciences Master Fund Ltd | 10% Owner | 1,800,000 | Jan 26, 2021 |
| Edelman Joseph | 10% Owner | 1,800,000 | Jan 26, 2021 |
| Angulo Gonzalez David | CEO | 853,098 | Oct 21, 2025 |
| Ventech Capital II | 10% Owner | 147,588 | May 8, 2014 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Jan 29, 2026 | Feb 2, 2026 | Macleod ivor | CFO | Neutral | 90.0 | +129,833 | 48.32% | ✗ | - |
| Jan 29, 2026 | Feb 2, 2026 | Sukenick Scott | Chief Legal Officer | Neutral | 90.0 | +129,833 | 29.20% | ✗ | - |
| Jan 29, 2026 | Feb 2, 2026 | Angulo Gonzalez David | CEO | Neutral | 90.0 | +391,333 | 45.87% | ✗ | - |
| Oct 17, 2025 | Oct 21, 2025 | Angulo Gonzalez David | CEO | Neutral | 82.5 | +32,500 | 3.96% | ✗ | - |
| Jun 26, 2025 | Jun 30, 2025 | Tinmouth Brian Philippe | Director | Neutral | 90.0 | +23,000 | 45.10% | ✗ | - |
| Jun 26, 2025 | Jun 30, 2025 | Macdonald Guy | Director | Neutral | 90.0 | +23,000 | 41.82% | ✗ | - |
| Jun 26, 2025 | Jun 30, 2025 | HASTINGS DAVID C | Director | Neutral | 90.0 | +23,000 | 49.80% | ✗ | - |
| Jun 26, 2025 | Jun 30, 2025 | HANHAM ANN | Director | Neutral | 90.0 | +23,000 | 49.33% | ✗ | - |
| Jun 26, 2025 | Jun 30, 2025 | GILMAN STEVEN C | Director | Neutral | 90.0 | +23,000 | 48.94% | ✗ | - |
| Jun 26, 2025 | Jun 30, 2025 | ANIDO ARMANDO | Director | Neutral | 90.0 | +23,000 | 47.92% | ✗ | - |
| Apr 9, 2025 | Apr 10, 2025 | Angulo Gonzalez David | CEO | Neutral | 82.5 | +23,000 | 2.90% | ✗ | - |
| Mar 19, 2025 | Mar 20, 2025 | Angulo Gonzalez David | CEO | Neutral | 77.5 | +18,800 | 2.43% | ✗ | - |
| Jan 23, 2025 | Jan 27, 2025 | Sukenick Scott | Chief Legal Officer | Neutral | 90.0 | +92,511 | 26.88% | ✗ | - |
| Jan 23, 2025 | Jan 27, 2025 | Macleod ivor | CFO | Neutral | 90.0 | +92,511 | 55.01% | ✗ | - |
| Jan 23, 2025 | Jan 27, 2025 | Angulo Gonzalez David | CEO | Neutral | 90.0 | +262,927 | 51.77% | ✗ | - |
| Sep 12, 2024 | Sep 16, 2024 | Angulo Gonzalez David | CEO | Buy | 83.8 | +20,000 | 4.10% | ✗ | $27.4K |
| Jun 20, 2024 | Jun 21, 2024 | Macdonald Guy | Director | Neutral | 90.0 | +23,000 | 71.88% | ✗ | - |
| Jun 20, 2024 | Jun 21, 2024 | HASTINGS DAVID C | Director | Neutral | 90.0 | +23,000 | 99.21% | ✗ | - |
| Jun 20, 2024 | Jun 21, 2024 | GILMAN STEVEN C | Director | Neutral | 90.0 | +23,000 | 95.83% | ✗ | - |
| Jun 20, 2024 | Jun 21, 2024 | Tinmouth Brian Philippe | Director | Neutral | 90.0 | +23,000 | 82.14% | ✗ | - |
| Jun 20, 2024 | Jun 21, 2024 | ANIDO ARMANDO | Director | Neutral | 90.0 | +23,000 | 92.00% | ✗ | - |
| Jun 20, 2024 | Jun 21, 2024 | HANHAM ANN | Director | Neutral | 90.0 | +23,000 | 97.37% | ✗ | - |
| Feb 16, 2024 | Feb 16, 2024 | Sukenick Scott | Chief Legal Officer | Sell | 46.3 | -15,179 | -4.32% | ✗ | $24.7K |
| Jan 26, 2024 | Jan 30, 2024 | Angulo Gonzalez David | CEO | Neutral | 90.0 | +290,590 | 153.52% | ✗ | - |
| Jan 26, 2024 | Jan 30, 2024 | Macleod ivor | CFO | Neutral | 90.0 | +143,675 | 870.23% | ✗ | - |
| Jan 26, 2024 | Jan 30, 2024 | Sukenick Scott | Chief Legal Officer | Neutral | 90.0 | +143,675 | 69.17% | ✗ | - |
| Jun 15, 2023 | Jun 23, 2023 | Tinmouth Brian Philippe | Director | Neutral | 90.0 | +10,000 | 55.56% | ✗ | - |
| Jun 15, 2023 | Jun 23, 2023 | ANIDO ARMANDO | Director | Neutral | 90.0 | +10,000 | 66.67% | ✗ | - |
| Jun 15, 2023 | Jun 23, 2023 | GILMAN STEVEN C | Director | Neutral | 90.0 | +10,000 | 71.43% | ✗ | - |
| Jun 15, 2023 | Jun 23, 2023 | HANHAM ANN | Director | Neutral | 90.0 | +10,000 | 73.41% | ✗ | - |
| Jun 15, 2023 | Jun 23, 2023 | HASTINGS DAVID C | Director | Neutral | 90.0 | +10,000 | 75.86% | ✗ | - |
| Jun 15, 2023 | Jun 23, 2023 | Macdonald Guy | Director | Neutral | 90.0 | +10,000 | 45.45% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | HASTINGS DAVID C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | Tinmouth Brian Philippe | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | HANHAM ANN | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | GILMAN STEVEN C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | ANIDO ARMANDO | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 15, 2023 | Jun 20, 2023 | Macdonald Guy | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 15, 2023 | May 17, 2023 | Sukenick Scott | Chief Legal Officer | Neutral | 90.0 | +50,000 | 32.55% | ✗ | - |
| Jan 27, 2023 | Jan 31, 2023 | Sukenick Scott | General Counsel | Neutral | 90.0 | +100,000 | 186.57% | ✗ | - |
| Jan 1, 2023 | Jan 3, 2023 | Angulo Gonzalez David | CEO | Neutral | 90.0 | +110,000 | 146.31% | ✗ | - |
| Oct 24, 2022 | Oct 26, 2022 | Macleod ivor | CFO | Neutral | 90.0 | +15,000 | 100.00% | ✗ | - |
| Oct 26, 2022 | Macleod ivor | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jun 17, 2022 | Jun 22, 2022 | Tinmouth Brian Philippe | Director | Neutral | 90.0 | +10,000 | 125.00% | ✗ | - |
| Jun 17, 2022 | Jun 22, 2022 | Macdonald Guy | Director | Neutral | 90.0 | +10,000 | 83.33% | ✗ | - |
| Jun 17, 2022 | Jun 22, 2022 | HASTINGS DAVID C | Director | Neutral | 90.0 | +10,000 | 314.17% | ✗ | - |
| Jun 17, 2022 | Jun 22, 2022 | HANHAM ANN | Director | Neutral | 90.0 | +10,000 | 276.09% | ✗ | - |
| Jun 17, 2022 | Jun 22, 2022 | GILMAN STEVEN C | Director | Neutral | 90.0 | +10,000 | 250.00% | ✗ | - |
| Jun 17, 2022 | Jun 22, 2022 | ANIDO ARMANDO | Director | Neutral | 90.0 | +10,000 | 200.00% | ✗ | - |
| Apr 26, 2022 | Apr 28, 2022 | Taglietti Marco | CEO | Buy | 95.0 | +75,000 | 38.06% | ✗ | $225K |
| Apr 26, 2022 | Apr 28, 2022 | Sukenick Scott | General Counsel | Buy | 86.3 | +3,500 | 7.00% | ✗ | $10.5K |
| Feb 4, 2022 | Feb 8, 2022 | Taglietti Marco | CEO | Neutral | 90.0 | +87,200 | 79.44% | ✗ | - |
| Feb 4, 2022 | Feb 8, 2022 | Sukenick Scott | General Counsel | Neutral | 90.0 | +40,700 | 442.44% | ✗ | - |
| Feb 4, 2022 | Feb 8, 2022 | Coyne Christine | Chief Commercial Officer | Neutral | 90.0 | +43,200 | 288.00% | ✗ | - |
| Feb 4, 2022 | Feb 8, 2022 | Angulo Gonzalez David | Chief Medical Officer | Neutral | 90.0 | +51,100 | 213.98% | ✗ | - |
| Dec 2, 2021 | HOFFMAN LAWRENCE R | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jun 16, 2021 | Jun 21, 2021 | Tinmouth Brian Philippe | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 16, 2021 | Jun 21, 2021 | Macdonald Guy | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 16, 2021 | Jun 21, 2021 | HASTINGS DAVID C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 16, 2021 | Jun 21, 2021 | HANHAM ANN | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 16, 2021 | Jun 21, 2021 | GILMAN STEVEN C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 16, 2021 | Jun 21, 2021 | ANIDO ARMANDO | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 10, 2021 | May 12, 2021 | Coyne Christine | Chief Commercial Officer | Neutral | 90.0 | +15,000 | 100.00% | ✗ | - |
| May 12, 2021 | Coyne Christine | Chief Commercial Officer | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jul 6, 2020 | Mar 31, 2021 | Tinmouth Brian Philippe | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 6, 2020 | Mar 31, 2021 | Macdonald Guy | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 6, 2020 | Mar 31, 2021 | HASTINGS DAVID C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 6, 2020 | Mar 31, 2021 | HANHAM ANN | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 6, 2020 | Mar 31, 2021 | GILMAN STEVEN C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 6, 2020 | Mar 31, 2021 | ANIDO ARMANDO | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 29, 2021 | Feb 2, 2021 | Taglietti Marco | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 29, 2021 | Feb 2, 2021 | Sukenick Scott | General Counsel | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 29, 2021 | Feb 2, 2021 | Francois Eric | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 29, 2021 | Feb 2, 2021 | Angulo Gonzalez David | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 20, 2021 | Jan 26, 2021 | PERCEPTIVE ADVISORS LLC | 10% Owner | Sell | 17.5 | -599,000 | -6.99% | ✗ | $4.7M |
| Jan 26, 2021 | PERCEPTIVE ADVISORS LLC | 10% Owner | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Dec 21, 2020 | Dec 23, 2020 | Tinmouth Brian Philippe | Director | Buy | 95.0 | +8,000 | 100.00% | ✗ | $50K |
| Dec 21, 2020 | Dec 23, 2020 | Taglietti Marco | CEO | Buy | 97.5 | +40,000 | 57.42% | ✗ | $250K |
| Dec 21, 2020 | Dec 23, 2020 | Sukenick Scott | General Counsel | Buy | 91.3 | +1,600 | 21.34% | ✗ | $10K |
| Dec 21, 2020 | Dec 23, 2020 | Macdonald Guy | Director | Buy | 95.0 | +8,000 | 200.00% | ✗ | $50K |
| Dec 21, 2020 | Dec 23, 2020 | HANHAM ANN | Director | Buy | 91.3 | +3,200 | 758.29% | ✗ | $20K |
| Dec 21, 2020 | Dec 23, 2020 | GILMAN STEVEN C | Director | Buy | 91.3 | +4,000 | 100.00% | ✗ | $25K |
| Dec 21, 2020 | Dec 23, 2020 | Francois Eric | CFO | Buy | 85.0 | +600 | 5.39% | ✗ | $3.8K |
| Dec 21, 2020 | Dec 23, 2020 | ANIDO ARMANDO | Director | Buy | 91.3 | +5,000 | 100.00% | ✗ | $31.3K |
| Dec 21, 2020 | Dec 23, 2020 | Angulo Gonzalez David | Chief Medical Officer | Buy | 86.3 | +1,600 | 7.21% | ✗ | $10K |
| Feb 15, 2020 | Dec 4, 2020 | Sukenick Scott | General Counsel | Sell | 46.3 | -3,396 | -16.32% | ✗ | $25.5K |
| Feb 15, 2020 | Dec 4, 2020 | Francois Eric | CFO | Sell | 46.3 | -4,459 | -14.86% | ✗ | $33.3K |
| Feb 15, 2020 | Dec 4, 2020 | Angulo Gonzalez David | Chief Medical Officer | Sell | 46.3 | -5,498 | -10.19% | ✗ | $41K |
| Jul 6, 2020 | Jul 8, 2020 | Tinmouth Brian Philippe | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 6, 2020 | Jul 8, 2020 | Macdonald Guy | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 6, 2020 | Jul 8, 2020 | HASTINGS DAVID C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 6, 2020 | Jul 8, 2020 | HANHAM ANN | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 6, 2020 | Jul 8, 2020 | GILMAN STEVEN C | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 6, 2020 | Jul 8, 2020 | ANIDO ARMANDO | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2020 | Feb 4, 2020 | Sukenick Scott | General Counsel | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2020 | Feb 4, 2020 | Francois Eric | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2020 | Feb 4, 2020 | Angulo Gonzalez David | Chief Medical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 31, 2020 | Feb 4, 2020 | Taglietti Marco | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 13, 2019 | Dec 17, 2019 | Tinmouth Brian Philippe | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 17, 2019 | Tinmouth Brian Philippe | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |