Septerna, Inc. (SEPN)

Latest Insider Confidence Score

2026Q1

49.3
Bearish

Company insider confidence (by quarter)

2024Q4 2026Q1

Largest shareholders

Insider Role (last 12 mo) Shares held Filed at
Third Rock Ventures VI, L.P. 10% Owner 2,872,956 Oct 28, 2024
Third Rock Ventures V, L.P. 10% Owner 2,872,956 Oct 28, 2024
Third Rock Ventures GP V, LP 10% Owner 2,872,956 Oct 28, 2024
Trv Gp V, Llc 10% Owner 2,872,956 Oct 28, 2024
Third Rock Ventures GP VI, L.P. 10% Owner 2,872,956 Oct 28, 2024

Recent buy/sell transactions

Exec date Filing date Insider Role Signal Confidence Shares % of shares Under plan? Amount (USD)
Mar 2, 2026 Mar 4, 2026 Shaikhly Samira Chief People Officer Sell 8.8 -70,453 -98.89% ✓ $2M
Feb 18, 2026 Feb 20, 2026 Bhatt Elizabeth COO Sell 42.5 -4,000 -2.24% ✓ $115.9K
Feb 6, 2026 Feb 10, 2026 Long Daniel D. SVP, Drug Discovery Neutral 52.5 - 0.00% ✗ -
Feb 6, 2026 Feb 10, 2026 Klein Uwe SVP, Biological Sciences Neutral 52.5 - 0.00% ✗ -
Feb 6, 2026 Feb 10, 2026 Shaikhly Samira Chief People Officer Neutral 52.5 - 0.00% ✗ -
Feb 6, 2026 Feb 10, 2026 Labrucherie Gil M CFO Neutral 52.5 - 0.00% ✗ -
Feb 6, 2026 Feb 10, 2026 Kim Jae B. Chief Medical Officer Neutral 52.5 - 0.00% ✗ -
Feb 6, 2026 Feb 10, 2026 Bhatt Elizabeth COO Neutral 52.5 - 0.00% ✗ -
Feb 6, 2026 Feb 10, 2026 Finer Jeffrey CEO Neutral 52.5 - 0.00% ✗ -
Feb 6, 2026 Feb 10, 2026 Wilson Mark Andrew Chief Legal Officer Neutral 52.5 - 0.00% ✗ -
Jan 15, 2026 Wilson Mark Andrew Chief Legal Officer Neutral 52.5 - 0.00% ✗ -
Nov 10, 2025 Nov 13, 2025 Long Daniel D. SVP, Drug Discovery Sell 22.5 -3,501 -3.63% ✗ $63.2K
Sep 25, 2025 Sep 29, 2025 Gottesdiener Keith Michael Director Neutral 52.5 - 0.00% ✗ -
Sep 29, 2025 Gottesdiener Keith Michael Director Neutral 52.5 - 0.00% ✗ -
Aug 18, 2025 Aug 19, 2025 Klein Uwe SVP, Biological Sciences Neutral 52.5 - 0.00% ✗ -
Aug 7, 2025 Aug 11, 2025 Shaikhly Samira Chief People Officer Neutral 52.5 - 0.00% ✗ -
Aug 7, 2025 Aug 11, 2025 Bhatt Elizabeth COO Neutral 52.5 - 0.00% ✗ -
Aug 7, 2025 Aug 11, 2025 Kim Jae B. Chief Medical Officer Neutral 52.5 - 0.00% ✗ -
Aug 7, 2025 Aug 11, 2025 Labrucherie Gil M CFO Neutral 52.5 - 0.00% ✗ -
Aug 7, 2025 Aug 11, 2025 Finer Jeffrey CEO Neutral 52.5 - 0.00% ✗ -
Aug 7, 2025 Aug 11, 2025 Long Daniel D. SVP, Drug Discovery Neutral 52.5 - 0.00% ✗ -
Aug 7, 2025 Aug 11, 2025 Klein Uwe SVP, Biological Sciences Neutral 52.5 - 0.00% ✗ -
Jun 17, 2025 Jun 20, 2025 RA CAPITAL MANAGEMENT, L.P. Director Neutral 52.5 - 0.00% ✗ -
Jun 17, 2025 Jun 20, 2025 Sharp Shalini Director Neutral 52.5 - 0.00% ✗ -
Jun 17, 2025 Jun 20, 2025 Tong Jeffrey K Director Neutral 52.5 - 0.00% ✗ -
Jun 17, 2025 Jun 20, 2025 Coulie Bernard Director Neutral 52.5 - 0.00% ✗ -
Jun 17, 2025 Jun 20, 2025 Simson Jake Director Neutral 52.5 - 0.00% ✗ -
Jun 17, 2025 Jun 20, 2025 Bassan Abraham Director Neutral 52.5 - 0.00% ✗ -
Jun 17, 2025 Jun 20, 2025 Ezekowitz Alan Director Neutral 52.5 - 0.00% ✗ -
Apr 2, 2025 Apr 4, 2025 Finer Jeffrey CEO Neutral 52.5 - 0.00% ✗ -
Mar 7, 2025 Mar 10, 2025 Ezekowitz Alan Director Buy 95.0 +13,319 12.79% ✗ $92.3K
Mar 4, 2025 Mar 6, 2025 Ezekowitz Alan Director Buy 97.5 +86,681 497.59% ✗ $515.9K
Feb 25, 2025 Feb 27, 2025 Finer Jeffrey CEO Buy 82.5 +17,000 2.25% ✗ $97K
Feb 25, 2025 Feb 27, 2025 Labrucherie Gil M CFO Buy 95.0 +10,000 33.33% ✗ $56.9K
Feb 24, 2025 Feb 26, 2025 Third Rock Ventures VI, L.P. 10% Owner Buy 60.0 +18,861 0.18% ✗ $113.1K
Feb 20, 2025 Feb 24, 2025 Third Rock Ventures VI, L.P. 10% Owner Buy 100.0 +1,040,342 11.11% ✗ $6.2M
Feb 19, 2025 Feb 21, 2025 Labrucherie Gil M CFO Buy 95.0 +30,000 100.00% ✗ $172.3K
Feb 7, 2025 Feb 7, 2025 Labrucherie Gil M CFO Neutral 52.5 - 0.00% ✗ -
Jan 7, 2025 Labrucherie Gil M CFO Neutral 52.5 - 0.00% ✗ -
Oct 28, 2024 Oct 30, 2024 RA CAPITAL MANAGEMENT, L.P. Director Buy 100.0 +4,170,000 147.57% ✗ $75.1M
Oct 28, 2024 Oct 28, 2024 Third Rock Ventures V, L.P. 10% Owner Buy 97.5 +650,000 7.46% ✗ $11.7M
Oct 24, 2024 Bhatt Elizabeth COO Neutral 52.5 - 0.00% ✗ -
Oct 24, 2024 Xiao Ran CFO Neutral 52.5 - 0.00% ✗ -
Oct 24, 2024 Kim Jae B. Chief Medical Officer Neutral 52.5 - 0.00% ✗ -
Oct 24, 2024 Klein Uwe SVP, Biological Sciences Neutral 52.5 - 0.00% ✗ -
Oct 24, 2024 Tong Jeffrey K Director Neutral 52.5 - 0.00% ✗ -
Oct 24, 2024 Shaikhly Samira Chief People Officer Neutral 52.5 - 0.00% ✗ -
Oct 24, 2024 Third Rock Ventures V, L.P. 10% Owner Neutral 52.5 - 0.00% ✗ -
Oct 24, 2024 RA CAPITAL MANAGEMENT, L.P. Director Neutral 52.5 - 0.00% ✗ -
Oct 24, 2024 Finer Jeffrey CEO Neutral 52.5 - 0.00% ✗ -
Oct 24, 2024 Ezekowitz Alan Director Neutral 52.5 - 0.00% ✗ -
Oct 24, 2024 Sharp Shalini Director Neutral 52.5 - 0.00% ✗ -
Oct 24, 2024 Simson Jake Director Neutral 52.5 - 0.00% ✗ -
Oct 24, 2024 Coulie Bernard Director Neutral 52.5 - 0.00% ✗ -
Oct 24, 2024 Bassan Abraham Director Neutral 52.5 - 0.00% ✗ -
Oct 24, 2024 Long Daniel D. SVP, Drug Discovery Neutral 52.5 - 0.00% ✗ -