2026Q1
| Insider | Role (last 12 mo) | Shares held | Filed at |
|---|---|---|---|
| Redmile Group, LLC | Director | 5,539,724 | Dec 6, 2024 |
| Green Jeremy | Director | 5,539,724 | Dec 6, 2024 |
| Orbimed Advisors Llc | Director | 3,073,298 | Sep 2, 2025 |
| OrbiMed Capital GP IX LLC | Director | 3,073,298 | Sep 2, 2025 |
| OrbiMed Genesis GP LLC | Director | 3,073,298 | Sep 2, 2025 |
| Exec date | Filing date | Insider | Role | Signal | Confidence | Shares | % of shares | Under plan? | Amount (USD) |
|---|---|---|---|---|---|---|---|---|---|
| Jan 25, 2026 | Jan 27, 2026 | Pandite Arundathy N. | Chief Medical Officer | Sell | 26.3 | -3,195 | -1.60% | ✗ | $13.3K |
| Jan 25, 2026 | Jan 27, 2026 | Stout Stephen | Officer | Sell | 37.5 | -593 | -0.72% | ✗ | $2.5K |
| Jan 25, 2026 | Jan 27, 2026 | DeYoung Casi | Chief Business Officer | Sell | 27.5 | -2,286 | -3.02% | ✗ | $9.5K |
| Jan 25, 2026 | Jan 27, 2026 | Neill Andrew R | CFO | Sell | 26.3 | -2,589 | -1.12% | ✗ | $10.7K |
| Jan 10, 2026 | Jan 13, 2026 | Stout Stephen | Officer | Sell | 26.3 | -4,153 | -4.81% | ✗ | $19.7K |
| Jan 10, 2026 | Jan 13, 2026 | DeYoung Casi | Chief Business Officer | Sell | 26.3 | -5,699 | -7.00% | ✗ | $27.1K |
| Jan 10, 2026 | Jan 13, 2026 | Shukla Abhinav A. | Chief Technical Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 10, 2026 | Jan 13, 2026 | Pandite Arundathy N. | Chief Medical Officer | Sell | 26.3 | -6,851 | -3.32% | ✗ | $32.5K |
| Jan 10, 2026 | Jan 13, 2026 | Neill Andrew R | CFO | Sell | 26.3 | -6,660 | -2.80% | ✗ | $31.6K |
| Jan 10, 2026 | Jan 13, 2026 | Schreiber Taylor | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Aug 25, 2025 | Sep 2, 2025 | ORBIMED ADVISORS LLC | Director | Buy | 100.0 | +6,306,127 | 100.00% | ✗ | $5.5M |
| Aug 25, 2025 | Sep 2, 2025 | Ashiya Mona | Director | Buy | 100.0 | +6,306,127 | 100.00% | ✗ | $5.5M |
| Sep 2, 2025 | ORBIMED ADVISORS LLC | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Aug 28, 2025 | Sep 2, 2025 | Ashiya Mona | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Aug 28, 2025 | Sep 2, 2025 | Baker Daniel G. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Sep 2, 2025 | Baker Daniel G. | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Sep 2, 2025 | Ashiya Mona | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Aug 25, 2025 | Aug 27, 2025 | Stout Stephen | Officer | Neutral | 90.0 | +12,805 | 17.43% | ✗ | - |
| Aug 25, 2025 | Aug 27, 2025 | Neill Andrew R | CFO | Neutral | 90.0 | +64,027 | 36.91% | ✗ | - |
| Aug 25, 2025 | Aug 27, 2025 | SIEGALL CLAY B | Director | Neutral | 90.0 | +128,054 | 100.00% | ✗ | - |
| Aug 25, 2025 | Aug 27, 2025 | Shukla Abhinav A. | Chief Technical Officer | Neutral | 85.0 | +5,122 | 6.73% | ✗ | - |
| Aug 25, 2025 | Aug 27, 2025 | Schreiber Taylor | CEO | Neutral | 67.5 | +25,610 | 0.95% | ✗ | - |
| Aug 25, 2025 | Aug 26, 2025 | Redmile Group, LLC | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 14, 2025 | Jul 16, 2025 | Lee Michael Stewart | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 14, 2025 | Jul 16, 2025 | Redmile Group, LLC | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 14, 2025 | Jul 16, 2025 | SIEGALL CLAY B | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 14, 2025 | Jul 16, 2025 | Sasser Amy Kate | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 14, 2025 | Jul 16, 2025 | Golumbeski George | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 14, 2025 | Jul 16, 2025 | Gibson Neil W | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 14, 2025 | Jul 16, 2025 | Brownstein Carrie | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 14, 2025 | Jul 16, 2025 | Brous Tyler | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jul 14, 2025 | Jul 16, 2025 | Boudreau Helen M | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 25, 2025 | Jan 28, 2025 | Shukla Abhinav A. | Chief Technical Officer | Sell | 27.5 | -2,261 | -2.98% | ✗ | $2.6K |
| Jan 25, 2025 | Jan 28, 2025 | DeYoung Casi | Chief Business Officer | Sell | 27.5 | -2,297 | -2.74% | ✗ | $2.7K |
| Jan 25, 2025 | Jan 28, 2025 | Pandite Arundathy N. | Chief Medical Officer | Sell | 27.5 | -3,211 | -1.53% | ✗ | $3.7K |
| Jan 28, 2025 | Jan 28, 2025 | Stout Stephen | Officer | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 28, 2025 | Jan 28, 2025 | Neill Andrew R | CFO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 28, 2025 | Jan 28, 2025 | Schreiber Taylor | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 10, 2025 | Jan 13, 2025 | Pandite Arundathy N. | Chief Medical Officer | Sell | 27.5 | -6,884 | -3.18% | ✗ | $8.2K |
| Jan 10, 2025 | Jan 13, 2025 | DeYoung Casi | Chief Business Officer | Sell | 27.5 | -5,727 | -6.40% | ✗ | $6.8K |
| Jan 10, 2025 | Jan 13, 2025 | Shukla Abhinav A. | Chief Technical Officer | Sell | 27.5 | -4,830 | -6.08% | ✗ | $5.7K |
| Dec 4, 2024 | Dec 6, 2024 | Redmile Group, LLC | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Oct 7, 2024 | Oct 8, 2024 | Schreiber Taylor | CEO | Buy | 78.8 | +36,500 | 1.38% | ✗ | $44.2K |
| Jun 27, 2024 | Jul 1, 2024 | Brous Tyler | Director | Buy | 83.8 | +8,416 | 3.66% | ✗ | $32.8K |
| Jun 26, 2024 | Jun 26, 2024 | Schreiber Taylor | CEO | Buy | 72.5 | +14,400 | 0.55% | ✗ | $50K |
| Jun 21, 2024 | Jun 21, 2024 | Lee Michael Stewart | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 21, 2024 | Jun 21, 2024 | Redmile Group, LLC | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 21, 2024 | Jun 21, 2024 | SIEGALL CLAY B | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 21, 2024 | Jun 21, 2024 | Sasser Amy Kate | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 21, 2024 | Jun 21, 2024 | Golumbeski George | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 21, 2024 | Jun 21, 2024 | Gibson Neil W | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 21, 2024 | Jun 21, 2024 | Boudreau Helen M | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 21, 2024 | Jun 21, 2024 | Brownstein Carrie | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 21, 2024 | Jun 21, 2024 | Brous Tyler | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 4, 2024 | Jun 5, 2024 | Schreiber Taylor | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 10, 2024 | May 14, 2024 | Stout Stephen | Officer | Sell | 26.3 | -967 | -1.30% | ✗ | $10.1K |
| Mar 28, 2024 | Apr 1, 2024 | Redmile Group, LLC | Director | Neutral | 52.5 | -4,425 | -0.08% | ✗ | - |
| Mar 6, 2024 | Mar 8, 2024 | Stout Stephen | Officer | Sell | 32.5 | -16,004 | -6.42% | ✓ | $168.5K |
| Mar 6, 2024 | Mar 8, 2024 | SIEGALL CLAY B | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 6, 2024 | Mar 8, 2024 | Sasser Amy Kate | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Mar 8, 2024 | SIEGALL CLAY B | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Mar 8, 2024 | Sasser Amy Kate | Director | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jan 30, 2024 | Jan 31, 2024 | Pandite Arundathy N. | Chief Medical Officer | Sell | 26.3 | -2,920 | -1.33% | ✗ | $29.2K |
| Jan 30, 2024 | Jan 31, 2024 | Stout Stephen | Officer | Sell | 37.5 | -593 | -0.74% | ✗ | $5.9K |
| Jan 30, 2024 | Jan 31, 2024 | Shukla Abhinav A. | Chief Technical Officer | Sell | 26.3 | -2,290 | -2.80% | ✗ | $22.9K |
| Jan 30, 2024 | Jan 31, 2024 | DeYoung Casi | Chief Business Officer | Sell | 26.3 | -2,008 | -2.19% | ✗ | $20.1K |
| Jan 10, 2024 | Jan 16, 2024 | Shukla Abhinav A. | Chief Technical Officer | Neutral | 90.0 | +33,425 | 69.21% | ✗ | - |
| Jan 10, 2024 | Jan 16, 2024 | Stout Stephen | Officer | Neutral | 90.0 | +49,050 | 158.87% | ✗ | - |
| Jan 10, 2024 | Jan 16, 2024 | DeYoung Casi | Chief Business Officer | Sell | 91.3 | +44,617 | 95.17% | ✗ | $16K |
| Jan 10, 2024 | Jan 16, 2024 | Neill Andrew R | CFO | Sell | 97.5 | +29,030 | 20.10% | ✗ | $274.9K |
| Jan 10, 2024 | Jan 16, 2024 | Pandite Arundathy N. | Chief Medical Officer | Sell | 91.3 | +43,488 | 24.74% | ✗ | $30.1K |
| Jan 12, 2024 | Jan 16, 2024 | Schreiber Taylor | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Dec 21, 2023 | Dec 26, 2023 | Redmile Group, LLC | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 26, 2023 | May 31, 2023 | Redmile Group, LLC | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 26, 2023 | May 31, 2023 | Lee Michael Stewart | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 26, 2023 | May 31, 2023 | Boudreau Helen M | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 26, 2023 | May 31, 2023 | Golumbeski George | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 26, 2023 | May 31, 2023 | Gibson Neil W | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 26, 2023 | May 31, 2023 | Brownstein Carrie | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 26, 2023 | May 31, 2023 | Brous Tyler | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| May 10, 2023 | May 12, 2023 | Stout Stephen | Officer | Neutral | 90.0 | +15,900 | 106.18% | ✗ | - |
| Mar 31, 2023 | Stout Stephen | Officer | Neutral | 52.5 | - | 0.00% | ✗ | - | |
| Jan 25, 2023 | Jan 27, 2023 | Neill Andrew R | CFO | Neutral | 90.0 | +34,925 | 31.90% | ✗ | - |
| Jan 25, 2023 | Jan 27, 2023 | Thomson Erin Ator | General Counsel | Neutral | 90.0 | +24,125 | 30.51% | ✗ | - |
| Jan 25, 2023 | Jan 27, 2023 | Shukla Abhinav A. | Chief Technical Officer | Neutral | 90.0 | +26,100 | 124.33% | ✗ | - |
| Jan 25, 2023 | Jan 27, 2023 | Pandite Arundathy N. | Chief Medical Officer | Neutral | 90.0 | +37,875 | 27.46% | ✗ | - |
| Jan 25, 2023 | Jan 27, 2023 | DeYoung Casi | Chief Business Officer | Neutral | 90.0 | +27,100 | 137.01% | ✗ | - |
| Jan 25, 2023 | Jan 27, 2023 | Schreiber Taylor | CEO | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jan 10, 2023 | Jan 12, 2023 | DeYoung Casi | Chief Business Officer | Sell | 27.5 | -1,583 | -7.41% | ✗ | $4.8K |
| Jan 10, 2023 | Jan 12, 2023 | Pandite Arundathy N. | Chief Medical Officer | Sell | 27.5 | -2,987 | -2.12% | ✗ | $9.1K |
| Jan 10, 2023 | Jan 12, 2023 | Shukla Abhinav A. | Chief Technical Officer | Sell | 27.5 | -1,933 | -8.43% | ✗ | $5.9K |
| Jun 8, 2022 | Jun 10, 2022 | Redmile Group, LLC | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 8, 2022 | Jun 10, 2022 | Lee Michael Stewart | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 8, 2022 | Jun 10, 2022 | Brous Tyler | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 8, 2022 | Jun 10, 2022 | Brownstein Carrie | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 8, 2022 | Jun 10, 2022 | Boudreau Helen M | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 8, 2022 | Jun 10, 2022 | Gibson Neil W | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Jun 8, 2022 | Jun 10, 2022 | Golumbeski George | Director | Neutral | 52.5 | - | 0.00% | ✗ | - |
| Apr 26, 2022 | Apr 27, 2022 | Golumbeski George | Director | Buy | 95.0 | +28,330 | 107.79% | ✗ | $102.8K |
| Apr 21, 2022 | Apr 26, 2022 | Golumbeski George | Director | Buy | 95.0 | +26,283 | 100.00% | ✗ | $97K |